Infectious agents and age-related neurodegenerative disorders
نویسندگان
چکیده
منابع مشابه
B vitamins and berries and age-related neurodegenerative disorders.
OBJECTIVES To assess the effects, associations, mechanisms of action, and safety of B vitamins and, separately, berries and their constituents on age-related neurocognitive disorders-primarily Alzheimer's (AD) and Parkinson's disease (PD). DATA SOURCES MEDLINE and CAB Abstracts. Additional studies were identified from reference lists and technical experts. REVIEW METHODS Vitamins B1, B2, B6...
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Aging is the major risk factor for numerous brain diseases. This is especially true for Alzheimer's disease (AD), a peculiar neurodegenerative disorder in that it results from the synergy of two simultaneous but distinct degenerating processes: A beta and tau pathologies. For AD, and for most neurodegenerative disorders, aggregation of full length or truncated proteins, in neurons or glial cell...
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Brain-derived neurotrophic factor (BDNF) and serotonin (5-hydroxytryptamine, 5-HT) are known to regulate synaptic plasticity, neurogenesis and neuronal survival in the adult brain. These two signals co-regulate one another such that 5-HT stimulates the expression of BDNF, and BDNF enhances the growth and survival of 5-HT neurons. Impaired 5-HT and BDNF signaling is central to depression and anx...
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1 Russian Academy of Medical Sciences, Moscow, Russia 2 Department of Health Information Management, Louisiana State University, Ruston, LA, USA 3 Department of Neurology, Louisiana State University Health Science Center, New Orleans, LA, USA 4 LSU Neuroscience Center and Department of Ophthalmology, Louisiana State University Health Science Center, New Orleans, LA, USA *Correspondence: wlukiw@...
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ژورنال
عنوان ژورنال: Ageing Research Reviews
سال: 2004
ISSN: 1568-1637
DOI: 10.1016/j.arr.2003.08.005